GEO2Enrichr: browser extension and server app to extract gene sets from GEO and analyze them for biological functions.

ABSTRACT:

Motivation

Identification of differentially expressed genes is an important step in extracting knowledge from gene expression profiling studies. The raw expression data from microarray and other high-throughput technologies is deposited into the Gene Expression Omnibus (GEO) and served as Simple Omnibus Format in Text (SOFT) files. However, to extract and analyze differentially expressed genes from GEO requires significant computational skills.

Results

Here we introduce GEO2Enrichr, a browser extension for extracting differentially expressed gene sets from GEO and analyzing those sets with Enrichr, an independent gene set enrichment analysis tool containing over 70 000 annotated gene sets organized into 75 gene-set libraries. GEO2Enrichr adds JavaScript code to GEO web-pages

SUBMITTER: Gundersen GW 

PROVIDER: S-EPMC4607730 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature