Manganese-Mediated Coupling Reaction of Vinylarenes and Aliphatic Alcohols.

ABSTRACT: Alcohols and alkenes are the most abundant and commonly used organic building blocks in the large-scale chemical synthesis. Herein, this is the first time to report a novel and operationally simple coupling reaction of vinylarenes and aliphatic alcohols catalyzed by manganese in the presence of TBHP (tert-butyl hydroperoxide). This coupling reaction provides the oxyalkylated products of vinylarenes with good regioselectivity and accomplishes with the principles of step-economies. A possible reaction mechanism has also been proposed.

SUBMITTER: Zhang W 

PROVIDER: S-EPMC4607950 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature