Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.

ABSTRACT: Understanding the genetic basis of phenotypic diversity is a challenge in contemporary biology. Domestication provides a model for unravelling aspects of the genetic basis of stress sensitivity. The ancestral Red Junglefowl (RJF) exhibits greater fear-related behaviour and a more pronounced HPA-axis reactivity than its domesticated counterpart, the White Leghorn (WL). By comparing hormones (plasmatic) and adrenal global gene transcription profiles between WL and RJF in response to an acute stress event, we investigated the molecular basis for the altered physiological stress responsiveness in domesticated chickens. Basal levels of pregnenolone and dehydroepiandrosterone as well as corticosterone response were lower in WL. Microarray analysis of gene expression in adrenal glands showed a si

SUBMITTER: Fallahsharoudi A 

PROVIDER: S-EPMC4608001 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature