Health-Related Quality of Life of Young Adults Treated with Recombinant Human Growth Hormone during Childhood.

ABSTRACT:

Background

Since recombinant human growth hormone (rhGH) became available in 1985, the spectrum of indications has broadened and the number of treated patients increased. However, long-term health-related quality of life (HRQoL) after childhood rhGH treatment has rarely been documented. We assessed HRQoL and its determinants in young adults treated with rhGH during childhood.

Methodology/principal findings

For this study, we retrospectively identified former rhGH patients in 11 centers of paediatric endocrinology, including university hospitals and private practices. We sent a questionnaire to all patients treated with rhGH for any diagnosis, who were older than 18 years, and who resided in Switzerland at time of the survey. Three hundred participants (58% of 514 eligible) r

SUBMITTER: Sommer G 

PROVIDER: S-EPMC4608786 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature