Bacterial transcriptome reorganization in thermal adaptive evolution.

ABSTRACT:

Background

Evolution optimizes a living system at both the genome and transcriptome levels. Few studies have investigated transcriptome evolution, whereas many studies have explored genome evolution in experimentally evolved cells. However, a comprehensive understanding of evolutionary mechanisms requires knowledge of how evolution shapes gene expression. Here, we analyzed Escherichia coli strains acquired during long-term thermal adaptive evolution.

Results

Evolved and ancestor Escherichia coli cells were exponentially grown under normal and high temperatures for subsequent transcriptome analysis. We found that both the ancestor and evolved cells had comparable magnitudes of transcriptional change in response to heat shock, although the evolutionary progression of their exp

SUBMITTER: Ying BW 

PROVIDER: S-EPMC4609109 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature