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M-Protein Analysis of Streptococcus pyogenes Isolates Associated with Acute Rheumatic Fever in New Zealand.

ABSTRACT: We applied an emm cluster typing system to group A Streptococcus strains in New Zealand, including those associated with acute rheumatic fever (ARF). We observed few so-called rheumatogenic emm types but found a high proportion of emm types previously associated with pyoderma, further suggesting a role for skin infection in ARF.

SUBMITTER: Williamson DA 

PROVIDER: S-EPMC4609735 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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M-Protein Analysis of Streptococcus pyogenes Isolates Associated with Acute Rheumatic Fever in New Zealand.

Williamson Deborah A DA   Smeesters Pierre R PR   Steer Andrew C AC   Steemson John D JD   Ng Adrian C H AC   Proft Thomas T   Fraser John D JD   Baker Michael G MG   Morgan Julie J   Carter Philip E PE   Moreland Nicole J NJ  

Journal of clinical microbiology 20150819 11

We applied an emm cluster typing system to group A Streptococcus strains in New Zealand, including those associated with acute rheumatic fever (ARF). We observed few so-called rheumatogenic emm types but found a high proportion of emm types previously associated with pyoderma, further suggesting a role for skin infection in ARF. ...[more]

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