Poly (3, 4-ethylenedioxythiophene)-ionic liquid coating improves neural recording and stimulation functionality of MEAs.

ABSTRACT: In vivo multi-electrode arrays (MEAs) can sense electrical signals from a small set of neurons or modulate neural activity through micro-stimulation. Electrode's geometric surface area (GSA) and impedance are important for both unit recording and neural stimulation. Smaller GSA is preferred due to enhanced selectivity of neural signal, but it tends to increase electrode impedance. Higher impedance leads to increased electrical noise and signal loss in single unit neural recording. It also yields a smaller charge injection window for safe neural stimulation. To address these issues, poly (3, 4-ethylenedioxythiophene) - ionic liquid (PEDOT-IL) conducting polymers were electrochemically polymerized on the surface of the microelectrodes. The PEDOT-IL coating reduced the electrode impedance mod

SUBMITTER: Du ZJ 

PROVIDER: S-EPMC4610193 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature