Recurrence of autism spectrum disorders in full- and half-siblings and trends over time: a population-based cohort study.

ABSTRACT:

Importance

To date, this is the first population-based study to examine the recurrence risk for autism spectrum disorders (ASDs), including time trends, and the first study to consider the ASDs recurrence risk for full- and half-siblings.

Objectives

To estimate the relative recurrence risk for ASDs in a Danish population, including recurrence in full- and half-siblings, and to examine time trends in ASDs relative to the recurrence risk.

Design, setting, and participants

Population-based cohort study in Denmark. All children (about 1.5 million) born in Denmark between January 1, 1980, and December 31, 2004, were identified and followed up to December 31, 2010. We identified a maternal sibling subcohort derived from mothers with at least 2 children and a paternal siblin

SUBMITTER: Gronborg TK 

PROVIDER: S-EPMC4610344 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature