Effects of early vitamin D deficiency rickets on bone and dental health, growth and immunity.

ABSTRACT: Vitamin D deficiency is associated with adverse health outcomes, including impaired bone growth, gingival inflammation and increased risk for autoimmune disease, but the relationship between vitamin D deficiency rickets in childhood and long-term health has not been studied. In this study, we assessed the effect of early vitamin D deficiency on growth, bone density, dental health and immune function in later childhood to determine if children previously diagnosed with rickets were at greater risk of adverse health outcomes compared with healthy children. We measured serum 25-hydroxyvitamin D, calcium, parathyroid hormone, bone mineral density, anthropometric measures, dietary habits, dental health, general health history, and markers of inflammation in 14 previously diagnosed rickets case

SUBMITTER: Zerofsky M 

PROVIDER: S-EPMC4610869 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature