Expression of tumor related genes NGX6, NAG-7, BRD7 in gastric and colorectal cancer.

ABSTRACT: AIM:NGX6, NAG-7 and BRD7 genes are tumor related genes, which have been newly cloned by positional candidate cloning strategy. This study was designed to investigate the expression levels of NGX6, NAG-7 and BRD7 genes in human gastric and colorectal cancer tissues, and their corresponding normal tissues, and to investigate whether these genes play a role in the pathogenesis of gastric and colorectal cancers. METHODS:Reverse transcription-polymerase chain reaction (RT-PCR), dot hybridization and Northern blot analysis were used to compare the expression levels of NGX6, NAG-7 and BRD7 genes in 34 gastric cancer tissues and 34 colorectal cancer tissues with their corresponding normal tissues of the same patients, respectively. RESULTS:Among the 34 colorectal cancer specimens and the 34 gastri

SUBMITTER: Zhang XM 

PROVIDER: S-EPMC4611532 | biostudies-literature | 2003 Aug

REPOSITORIES: biostudies-literature