Gene Expression Variations of Red-White Skin Coloration in Common Carp (Cyprinus carpio).

ABSTRACT: Teleosts have more types of chromatophores than other vertebrates and the genetic basis for pigmentation is highly conserved among vertebrates. Therefore, teleosts are important models to study the mechanism of pigmentation. Although functional genes and genetic variations of pigmentation have been studied, the mechanisms of different skin coloration remains poorly understood. The koi strain of common carp has various colors and patterns, making it a good model for studying the genetic basis of pigmentation. We performed RNA-sequencing for red skin and white skin and identified 62 differentially expressed genes (DEGs). Most of them were validated with RT-qPCR. The up-regulated DEGs in red skin were enriched in Kupffer's vesicle development while the up-regulated DEGs in white skin were inv

SUBMITTER: Li XM 

PROVIDER: S-EPMC4613254 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature