The Current Role of Omega-3 Fatty Acids in the Management of Atrial Fibrillation.

ABSTRACT:

Background

The main dietary source of omega-3 polyunsaturated fatty acids (n-3 PUFA) is fish, which contains eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In the present manuscript, we aimed to review the current evidence regarding the clinical role of n-3 PUFA in the prevention of atrial fibrillation (AF) and the possible underlying mechanisms.

Methods

A literature search based on PubMed listings was performed using "Omega-3 fatty acids" and "atrial fibrilation" as key search terms.

Results

n-3 PUFA have been shown to attenuate structural atrial remodeling, prolong atrial effective refractory period through the prevention of reentry and suppress ectopic firing from pulmonary veins. Dietary fish intake has been found to have no effect on the incidence of

SUBMITTER: Christou GA 

PROVIDER: S-EPMC4613340 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature