Persistence of Ebola Virus in Sterilized Wastewater.

ABSTRACT: In the wake of the ongoing 2014/2015 Ebola virus outbreak, significant questions regarding the appropriate handling of Ebola virus-contaminated liquid waste remain, including the persistence of Ebola virus in wastewater. To address these uncertainties, we evaluated the persistence of Ebola virus spiked in sterilized domestic sewage. The viral titer decreased approximately 99% within the first test day from an initial viral titer of 10⁶ TCID₅₀ mL^-1; however, it could not be determined if this initial rapid decrease was due to aggregation or inactivation of the viral particles. The subsequent viral titer decrease was less rapid, and infectious Ebola virus particles persisted for all 8 days of the test. The inactivation constant (k) was determined to be

SUBMITTER: Bibby K 

PROVIDER: S-EPMC4613737 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature