AASLD clinical practice guidelines: a critical review of scientific evidence and evolving recommendations.

ABSTRACT:

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The American Association for the Study of Liver Diseases (AASLD) practice guidelines provide recommendations in diagnosing and managing patients with liver disease from available scientific evidence in combination with expert consensus opinions. The aim was to systematically review the evolution of recommendations from AASLD guidelines and identify gaps limiting the evidence-based foundations of these guidelines. Initial and current AASLD guidelines published from January 1998 to August 2012 were reviewed. The AGREE II instrument was used to evaluate rigor and transparency of guideline development. The number of recommendations, distribution of grades (strength or certainty), classes (benefit versus risk), and types of recommendations were evaluated. Whenever possible, m

SUBMITTER: Koh C 

PROVIDER: S-EPMC4613804 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature