Sleep Disturbances and Glucose Metabolism in Older Adults: The Cardiovascular Health Study.

ABSTRACT:

Objective

We examined the associations of symptoms of sleep-disordered breathing (SDB), which was defined as loud snoring, stopping breathing for a while during sleep, and daytime sleepiness, and insomnia with glucose metabolism and incident type 2 diabetes in older adults.

Research design and methods

Between 1989 and 1993, the Cardiovascular Health Study recruited 5,888 participants ≥65 years of age from four U.S. communities. Participants reported SDB and insomnia symptoms yearly through 1989-1994. In 1989-1990, participants underwent an oral glucose tolerance test, from which insulin secretion and insulin sensitivity were estimated. Fasting glucose levels were measured in 1989-1990 and again in 1992-1993, 1994-1995, 1996-1997, and 1998-1999, and medication use was ascerta

SUBMITTER: Strand LB 

PROVIDER: S-EPMC4613916 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature