Energy Expenditure Responses to Fasting and Overfeeding Identify Phenotypes Associated With Weight Change.

ABSTRACT: Because it is unknown whether 24-h energy expenditure (EE) responses to dietary extremes will identify phenotypes associated with weight regulation, the aim of this study was to determine whether such responses to fasting or overfeeding are associated with future weight change. The 24-h EE during energy balance, fasting, and four different overfeeding diets with 200% energy requirements was measured in a metabolic chamber in 37 subjects with normal glucose regulation while they resided on our clinical research unit. Diets were given for 24 h each and included the following: (1) low protein (3%), (2) standard (50% carbohydrate, 20% protein), (3) high fat (60%), and (4) high carbohydrate (75%). Participants returned for follow-up 6 months after the initial measures. The decrease in 24-h EE d

SUBMITTER: Schlogl M 

PROVIDER: S-EPMC4613969 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature