High prevalence of raised lipoprotein(a) in patients with refractory angina.

ABSTRACT:

Background

Angina that is refractory to conventional medical therapy and revascularisation, remains challenging to manage and poses significant burden to patients. Elevated lipoprotein(a) [Lp(a)] has emerged as an important independent cardiovascular risk factor and predictor of adverse outcomes in atherosclerotic disease. The prevalence of raised Lp(a) amongst patients with refractory angina has not yet been defined.

Objective

To establish the prevalence of raised [Lp(a)] >500 mg/L in patients with refractory angina.

Methods

We conducted an epidemiological screening pilot study in 75 patients with refractory angina from a UK tertiary cardiac centre. We determined the proportion of the cohort with raised Lp(a) >500 mg/L using an isoform-insensitive method. In addition

SUBMITTER: Khan TZ 

PROVIDER: S-EPMC4614330 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature