Associations of prenatal maternal smoking with offspring hyperactivity: causal or confounded?

ABSTRACT:

Background

The relationship between prenatal tobacco exposure and hyperactivity remains controversial. To mitigate limitations of prior studies, we used a strategy involving comparison of maternal and paternal smoking reports in a historical sample where smoking during pregnancy was common.

Method

Data were drawn from a longitudinally followed subsample of the Child Health and Development Study (n = 1752), a population-based pregnancy cohort ascertained in 1961-1963 in California. Maternal prenatal smoking was common (33.4%). Maternal and paternal smoking patterns were assessed at three time points by mother report. Hyperactivity was assessed at the mean of age of 10 years based on mother report to a personality inventory.

Results

Unadjusted, maternal smoking during p

SUBMITTER: Keyes KM 

PROVIDER: S-EPMC4615686 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature