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Current stage in inflammatory bowel disease: What is next?


ABSTRACT: In recent years, the incidence of inflammatory bowel disease (IBD) has been on the rise, extending to countries where it was infrequent in the past. As a result, the gap between high and low incidence countries is decreasing. The disease, therefore, has an important economic impact on the healthcare system. Advances in recent years in pharmacogenetics and clinical pharmacology have allowed for the development of treatment strategies adjusted to the patient profile. Concurrently, new drugs aimed at inflammatory targets have been developed that may expand future treatment options. This review examines advances in the optimization of existing drug treatments and the development of novel treatment options for IBD.

SUBMITTER: Gomez-Gomez GJ 

PROVIDER: S-EPMC4616205 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Current stage in inflammatory bowel disease: What is next?

Gómez-Gómez Gonzalo Jesús GJ   Masedo Ángeles Á   Yela Carmen C   Martínez-Montiel Maria del Pilar Mdel P   Casís Begoña B  

World journal of gastroenterology 20151001 40


In recent years, the incidence of inflammatory bowel disease (IBD) has been on the rise, extending to countries where it was infrequent in the past. As a result, the gap between high and low incidence countries is decreasing. The disease, therefore, has an important economic impact on the healthcare system. Advances in recent years in pharmacogenetics and clinical pharmacology have allowed for the development of treatment strategies adjusted to the patient profile. Concurrently, new drugs aimed  ...[more]

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