Agenesis of internal carotid artery associated with isolated growth hormone deficiency: a case report and literature review.

ABSTRACT:

Background

Agenesis of the internal carotid artery (ICA) is a rare congenital abnormality, sporadically reported to be associated with a combined congenital hypopituitarism. Nevertheless, only a few cases have been extensively described, and none of these have been characterized by an isolated growth hormone (GH) deficiency.

Case presentation

Here, we describe a 17-year old boy referred to our hospital for fatigue, decreased muscle strength and severe headache reported after the cessation of rhGH treatment for a GH deficiency diagnosed at the age of 2 years and 3 months. Magnetic resonance imaging (MRI) showed an adenohypophyseal hypoplasia with a lack of posterior pituitary hyperintensity, whereas MRI angiography indicated the absence of a normal flow void in the left ICA.

SUBMITTER: Stagi S 

PROVIDER: S-EPMC4617709 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature