Risk of a Diagnosis of Dementia for Elderly Medicare Beneficiaries after Intensive Care.

ABSTRACT:

Background

Critical illness is likely associated with an increased risk of dementia, but the magnitude remains uncertain.

Methods

The cohort was a random 2.5% sample of Medicare beneficiaries who received intensive care in 2005 and survived to hospital discharge. Patients were matched with general population controls (age, sex, and race) with 3 yr of follow-up. The authors used an extended Cox model to assess the risk of a diagnosis of dementia, adjusting for the known risk factors for dementia, and the competing risk of death.

Results

Among 10,348 intensive care patients who survived to hospital discharge, dementia was newly diagnosed in 1,648 (15.0%) over the 3 yr of follow-up versus 12.2% in controls (incidence per 1,000 person-years, 73.6; 95% CI, 70.0 to 77.1 vs.

SUBMITTER: Guerra C 

PROVIDER: S-EPMC4618156 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature