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Visible light-initiated interfacial thiol-norbornene photopolymerization for forming islet surface conformal coating.

ABSTRACT: A cytocompatible visible light-mediated interfacial thiol-norbornene photopolymerization scheme was developed for creating hydrogel conformal coating on pancreatic islets. The step-growth thiol-norbornene reaction affords high consistency and tunability in gel coating thickness. Furthermore, isolated islets coated with thiol-norbornene gel maintained their viability and function in vitro.

SUBMITTER: Shih H 

PROVIDER: S-EPMC4618253 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Visible light-initiated interfacial thiol-norbornene photopolymerization for forming islet surface conformal coating.

Shih Han H   Mirmira Raghavendra G RG   Lin Chien-Chi CC  

Journal of materials chemistry. B 20150101

A cytocompatible visible light-mediated interfacial thiol-norbornene photopolymerization scheme was developed for creating hydrogel conformal coating on pancreatic islets. The step-growth thiol-norbornene reaction affords high consistency and tunability in gel coating thickness. Furthermore, isolated islets coated with thiol-norbornene gel maintained their viability and function <i>in vitro</i>. ...[more]

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