Zwitterionic amphiphile coated magnetofluorescent nanoparticles - synthesis, characterization and tumor cell targeting.

ABSTRACT: Magnetofluorescent nanoparticles (MFNPs) have recently attracted significant research interests due to their potential applications in biological manipulation and imaging. In this work, through a simple and fast self-assembling process, we first report the preparation of zwitterionic MFNPs (ZW-MFNPs) in the form of micelles using our newly synthesized zwitterionic amphiphiles, CuInS₂/ZnS quantum dots, and MnFe₂O₄ magnetic nanoparticles. ZW-MFNPs integrate both MnFe₂O₄ magnetic nanoparticles and CuInS₂/ZnS quantum dots in their hydrophobic cores and zwitterionic groups such as carboxybetaine and sulfobetaine on their hydrophilic shells. ZW-MFNPs possess dual imaging properties, high (Mn + Fe) recovery, excellent stability in

SUBMITTER: Demillo VG 

PROVIDER: S-EPMC4618671 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature