Danhong injection in the treatment of chronic stable angina: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Chronic stable angina is a leading cause of death worldwide. Danhong injection, a complementary alternative medicine for chronic stable angina, has been demonstrated to be effective in numerous studies and is widely prescribed to patients. However, the methodological quality of most prior studies was found to be, in general, low. Therefore, we designed this randomized controlled trial to evaluate the efficacy and safety of using Danhong injection to treat chronic stable angina.

Methods/design

This is a randomized multicentre, double-blind, placebo-controlled, adaptive clinical trial. A total of 870 patients meeting the eligibility criteria will be randomly assigned into either the Danhong injection or the placebo group in a 2:1 ratio. Participants will then underg

SUBMITTER: Wang PQ 

PROVIDER: S-EPMC4618746 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature