In silico hybridization enables transcriptomic illumination of the nature and evolution of Myxozoa.

ABSTRACT:

Background

The Myxozoa, a group of oligocellular, obligate endoparasites, has long been poorly understood in an evolutionary context. Recent genome-level sequencing techniques such as RNA-seq have generated large amounts of myxozoan sequence data, providing valuable insight into their evolutionary history. However, sequences from host tissue contamination are present in next-generation sequencing reactions of myxozoan tissue, and differentiating between the two has been inadequately addressed. In order to shed light on the genetic underpinnings of myxozoan biology, assembled contigs generated from these studies that derived from the myxozoan must be decoupled from transcripts derived from host tissue and other contamination. This study describes a pipeline for categorization of tra

SUBMITTER: Foox J 

PROVIDER: S-EPMC4619090 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature