Disrupted Ipsilateral Network Connectivity in Temporal Lobe Epilepsy.

ABSTRACT:

Objective

The current practice under which patients with refractory epilepsy are surgically treated is based mainly on the identification of specific cortical areas, mainly the epileptogenic zone, which is believed to be responsible for generation of seizures. A better understanding of the whole epileptic network and its components and properties is required before more effective and less invasive therapies can be developed. The aim of the present study was to partially characterize the evolution of the functional network during the preictal-ictal transition in partial seizures in patients with temporal lobe epilepsy (TLE).

Methods

Scalp and foramen ovale (FOE) recordings from twenty-two TLE patients were analyzed under the complex network perspective. The density of links,

SUBMITTER: Vega-Zelaya L 

PROVIDER: S-EPMC4619301 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature