Loss of a Conserved tRNA Anticodon Modification Perturbs Plant Immunity.

ABSTRACT: tRNA is the most highly modified class of RNA species, and modifications are found in tRNAs from all organisms that have been examined. Despite their vastly different chemical structures and their presence in different tRNAs, occurring in different locations in tRNA, the biosynthetic pathways of the majority of tRNA modifications include a methylation step(s). Recent discoveries have revealed unprecedented complexity in the modification patterns of tRNA, their regulation and function, suggesting that each modified nucleoside in tRNA may have its own specific function. However, in plants, our knowledge on the role of individual tRNA modifications and how they are regulated is very limited. In a genetic screen designed to identify factors regulating disease resistance and activation of defen

SUBMITTER: Ramirez V 

PROVIDER: S-EPMC4619653 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature