Natural products and drug discovery: a survey of stakeholders in industry and academia.

ABSTRACT:

Context

In recent decades, natural products have undisputedly played a leading role in the development of novel medicines. Yet, trends in the pharmaceutical industry at the level of research investments indicate that natural product research is neither prioritized nor perceived as fruitful in drug discovery programmes as compared with incremental structural modifications and large volume HTS screening of synthetics.

Aim

We seek to understand this phenomenon through insights from highly experienced natural product experts in industry and academia.

Method

We conducted a survey including a series of qualitative and quantitative questions related to current insights and prospective developments in natural product drug development. The survey was completed by a cross-secti

SUBMITTER: Amirkia V 

PROVIDER: S-EPMC4620409 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature