Association between angiotensinogen T174M polymorphism and ischemic stroke: A meta-analysis.

ABSTRACT:

Background

Numerous studies have evaluated the association between the angiotensinogen (AGT) T174M polymorphism and ischemic stroke(IS) risk. However, the specific association is still controversial.

Materials and methods

In order to explore this association more deeply, we performed a meta-analysis. All of the relevant studies were identified from PubMed, Embase, and Chinese National Knowledge Infrastructure database up to October 2014. Statistical analyses were conducted with STATA 12.0 software. Odds ratio (OR) with 95% confidence interval (CI) values were applied to evaluate the strength of the association.

Results

Six studies with 1290 cases and 1125 controls were included. No significant variation in IS risk was detected in any of the genetic models in the overa

SUBMITTER: Ou Z 

PROVIDER: S-EPMC4621658 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature