Lung function and exhaled nitric oxide in healthy unsedated African infants.

ABSTRACT:

Background and objective

Population-appropriate lung function reference data are essential to accurately identify respiratory disease and measure response to interventions. There are currently no reference data in African infants. The aim was to describe normal lung function in healthy African infants.

Methods

Lung function was performed on healthy South African infants enrolled in a birth cohort study, the Drakenstein child health study. Infants were excluded if they were born preterm or had a history of neonatal respiratory distress or prior respiratory tract infection. Measurements, made during natural sleep, included the forced oscillation technique, tidal breathing, exhaled nitric oxide and multiple breath washout measures.

Results

Three hundred sixty-three infan

SUBMITTER: Gray D 

PROVIDER: S-EPMC4623783 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature