Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results.

ABSTRACT:

Purpose

To evaluate the 2-year outcomes of uveitic macular edema.

Design

Longitudinal follow-up of a randomized cohort.

Participants

At baseline, 148 eyes of 117 patients enrolled in the Multicenter Uveitis Steroid Treatment (MUST) Trial had macular edema, and 134 eyes of 108 patients completed 2-year follow-up.

Methods

Patients enrolled in the study were randomized to either systemic immunosuppression or intravitreal fluocinolone acetonide implant therapy. Macular edema was defined as thickening of the retina (center point thickness≥240 μm) on time-domain optical coherence tomography (OCT) of macula.

Main outcome measures

Improvement in macular edema (≥20% reduction in central point thickness on OCT), resolution of macular edema (normalization of thickn

SUBMITTER: Tomkins-Netzer O 

PROVIDER: S-EPMC4624003 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature