Phenotypic and Molecular Evidence Suggests That Decrements in Morning and Evening Energy Are Distinct but Related Symptoms.

ABSTRACT:

Context

Little is known about energy levels in oncology patients and their family caregivers.

Objectives

This study sought to identify latent classes of participants, based on self-reported energy levels and evaluate for differences in phenotypic and genotypic characteristics between these classes.

Methods

Energy subscale scores from the Lee Fatigue Scale were used to determine latent class membership. Morning and evening energy scores were obtained just before, during, and for four months after the completion of radiation therapy. Genetic associations were evaluated for 15 proinflammatory and anti-inflammatory cytokine genes.

Results

Two latent classes with distinct morning energy trajectories were identified. Participants who were younger, female, not married

SUBMITTER: Aouizerat BE 

PROVIDER: S-EPMC4624028 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature