Longitudinal changes of angle configuration in primary angle-closure suspects: the Zhongshan Angle-Closure Prevention Trial.

ABSTRACT:

Objective

To determine longitudinal changes in angle configuration in the eyes of primary angle-closure suspects (PACS) treated by laser peripheral iridotomy (LPI) and in untreated fellow eyes.

Design

Longitudinal cohort study.

Participants

Primary angle-closure suspects aged 50 to 70 years were enrolled in a randomized, controlled clinical trial.

Methods

Each participant was treated by LPI in 1 randomly selected eye, with the fellow eye serving as a control. Angle width was assessed in a masked fashion using gonioscopy and anterior segment optical coherence tomography (AS-OCT) before and at 2 weeks, 6 months, and 18 months after LPI.

Main outcome measures

Angle width in degrees was calculated from Shaffer grades assessed under static gonioscopy. Angle c

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC4624262 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature