Exposure to environmental chemicals and heavy metals, and risk of pancreatic cancer.

ABSTRACT:

Purpose

Exposure to various chemicals and heavy metals has been associated with risk of different cancers; however, data on whether such exposures may increase the risk of pancreatic cancer (PC) are very limited and inconclusive. We examined PC risk with self-reported exposures to chemicals and heavy metals.

Methods

The design was a clinic-based, case-control study of data collected from 2000 to 2014 at Mayo Clinic in Rochester, Minnesota, USA. Cases were rapidly ascertained patients diagnosed with pancreatic ductal adenocarcinoma (n = 2,092). Controls were cancer-free patients in primary care clinics (n = 2,353), frequency-matched to cases on age, race, sex, and state/region of residence. Cases and controls completed identical risk factor questionnaires, which included yes/

SUBMITTER: Antwi SO 

PROVIDER: S-EPMC4624268 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature