Clinical and Functional Outcomes Associated With Myocardial Injury After Transfemoral and Transapical Transcatheter Aortic Valve Replacement: A Subanalysis From the PARTNER Trial (Placement of Aortic Transcatheter Valves).

ABSTRACT:

Objectives

This study sought to clarify the clinical and echocardiographic prognostic implication of myocardial injury after transcatheter aortic valve replacement (TAVR).

Background

The clinical significance of cardiac biomarker elevation after TAVR remains unclear.

Methods

Patients treated with TAVR in the PARTNER (Placement of Aortic Transcatheter Valves) trial were divided into tertiles (T1, T2, T3) based on the difference between the values on post-procedure day 1 and the baseline values of 2 cardiac biomarkers: cardiac troponin I (ΔcTnI); and creatine kinase-myocardial band (ΔCK-MB) fraction. Patients were stratified according to their access route: transfemoral (TF) (n = 1,840) or transapical (TA) (n = 1,173).

Results

At 30 days after TF-TAVR, patients i

SUBMITTER: Paradis JM 

PROVIDER: S-EPMC4624400 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature