Unknown

Dataset Information

0

NaNog: A pluripotency homeobox (master) molecule.


ABSTRACT: One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed "necessary", then at a specified time can differentiate into any type of cell. This fundamental process is required during organogenesis in foetal life and importantly during tissue repair in health and disease. Pluripotency is very tightly regulated, as any dysregulation can result in congenital defects, inability to repair damage, or cancer. Fuelled by the relatively recent interest in stem cell biology and tissue regeneration, the molecules implicated in regulating pluripotency have been the subject of extensive research. One of the important molecules involved in pluripotency, is NaNog, the subject of this article.

SUBMITTER: Allouba MH 

PROVIDER: S-EPMC4625207 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

altmetric image

Publications

NaNog: A pluripotency homeobox (master) molecule.

Allouba Mona H MH   ElGuindy Ahmed M AM   Krishnamoorthy Navaneethakrishnan N   Yacoub Magdi H MH   Aguib Yasmine E YE  

Global cardiology science & practice 20151015 3


One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed "necessary", then at a specified time can differentiate into any type of cell. This fundamental process is required during organogenesis in foetal life and importantly during tissue repair in health and disease. Pluripotency is very tightly regulated, as any dysregulation can result in congenital defects, inability to repair damage, or cancer. Fue  ...[more]

Similar Datasets

| S-EPMC4857071 | biostudies-literature
| S-EPMC2687465 | biostudies-literature
| S-EPMC3925756 | biostudies-literature
| S-EPMC3025321 | biostudies-literature
| S-EPMC5425684 | biostudies-literature
| S-EPMC2359802 | biostudies-other
| S-EPMC3606645 | biostudies-literature