Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study.

ABSTRACT:

Background

Adherence to a Mediterranean-type diet is linked to a lower risk of mortality and chronic disease, but the association with the progression of age-related macular degeneration (AMD) and genetic susceptibility is unknown.

Objective

We examined the association of adherence to the Mediterranean diet and genetic susceptibility with progression to advanced AMD.

Design

Among 2525 subjects in the AREDS (Age-Related Eye Disease Study), 1028 eyes progressed to advanced AMD over 13 y. Baseline data for demographic and behavioral covariates were collected by using questionnaires. Dietary data were collected from food-frequency questionnaires. The alternate Mediterranean diet (aMeDi) score (range: 0-9) was constructed from individual intakes of vegetables, fruit, legum

SUBMITTER: Merle BM 

PROVIDER: S-EPMC4625588 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature