Articular Cartilage of the Human Knee Joint: In Vivo Multicomponent T2 Analysis at 3.0 T.

ABSTRACT:

Purpose

To compare multicomponent T2 parameters of the articular cartilage of the knee joint measured by using multicomponent driven equilibrium single-shot observation of T1 and T2 (mcDESPOT) in asymptomatic volunteers and patients with osteoarthritis.

Materials and methods

This prospective study was performed with institutional review board approval and with written informed consent from all subjects. The mcDESPOT sequence was performed in the knee joint of 13 asymptomatic volunteers and 14 patients with osteoarthritis of the knee. Single-component T2 (T2(Single)), T2 of the fast-relaxing water component (T2F) and of the slow-relaxing water component (T2S), and the fraction of the fast-relaxing water component (F(F)) of cartilage were measured. Wilcoxon rank-sum tests and

SUBMITTER: Liu F 

PROVIDER: S-EPMC4627437 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature