Type 1 diabetes patients have lower strength in femoral bone determined by quantitative computed tomography: A cross-sectional study.

ABSTRACT:

Aims/introduction

Previous studies have reported osteoporosis measured by dual-energy X-ray absorptiometry in younger patients with type 1 diabetes. Limitations of 2-D imaging, however, limit the precision of dual-energy X-ray absorptiometry for the measurement of bone mineral density and bone strength.

Materials and methods

Three-dimensional quantitative computed tomography was used to calculate volumetric-bone mineral density (vBMD) and strength in femoral bone subfractions. A total of 17 male type 1 diabetes patients and 18 sex-matched healthy controls aged from 18 to 49 years were investigated in the present cross-sectional study. Patients with overt nephropathy were excluded.

Results

Type 1 diabetes patients had significantly lower cortical vBMD in the femoral ne

SUBMITTER: Ishikawa K 

PROVIDER: S-EPMC4627551 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature