Minireview: Emerging Roles for Extracellular Vesicles in Diabetes and Related Metabolic Disorders.

ABSTRACT: Extracellular vesicles (EVs), membrane-contained vesicles released by most cell types, have attracted a large amount of research interest over the past decade. Because of their ability to transfer cargo via regulated processes, causing functional impacts on recipient cells, these structures may play important roles in cell-cell communication and have implications in the physiology of numerous organ systems. In addition, EVs have been described in most human biofluids and have wide potential as relatively noninvasive biomarkers of various pathologic conditions. Specifically, EVs produced by the pancreatic β-cell have been demonstrated to regulate physiologic and pathologic responses to β-cell stress, including β-cell proliferation and apoptosis. β-Cell EVs are also capable of interacting wi

SUBMITTER: Lakhter AJ 

PROVIDER: S-EPMC4627606 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature