Changes of lung tumour volume on CT - prediction of the reliability of assessments.

ABSTRACT:

Background

For oncological evaluations, quantitative radiology gives clinicians significant insight into patients' response to therapy. In regard to the Response Evaluation Criteria in Solid Tumours (RECIST), the classification of disease evolution partly consists in applying thresholds to the measurement of the relative change of tumour. In the case of tumour volumetry, response thresholds have not yet been established. This study proposes and validates a model for calculating thresholds for the detection of minimal tumour change when using the volume of pulmonary lesions on CT as imaging biomarker.

Methods

Our work is based on the reliability analysis of tumour volume measurements documented by the Quantitative Imaging Biomarker Alliance. Statistics of measurements were en

SUBMITTER: Beaumont H 

PROVIDER: S-EPMC4628325 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature