A patient self-collection method for longitudinal monitoring of respiratory virus infection in solid organ transplant recipients.

ABSTRACT:

Background

Methods for the longitudinal study of respiratory virus infections are cumbersome and limit our understanding of the natural history of these infections in solid organ transplant (SOT) recipients.

Objectives

To assess the feasibility and patient acceptability of self-collected foam nasal swabs for detection of respiratory viruses in SOT recipients and to define the virologic and clinical course.

Study design

We prospectively monitored the course of symptomatic respiratory virus infection in 18 SOT patients (14 lung, 3 liver, and 1 kidney) using patient self-collected swabs.

Results

The initial study sample was positive in 15 patients with the following respiratory viruses: rhinovirus (6), metapneumovirus (1), coronavirus (2), respiratory syncytial vi

SUBMITTER: Preiksaitis CM 

PROVIDER: S-EPMC4629250 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature