Predictors of participant retention in infertility treatment trials.

ABSTRACT:

Objective

To identify variables associated with retention (or dropout) in infertility clinical trials. Retention of subjects in randomized controlled clinical trials (RCTs) has received considerable attention, but there have been few consistent findings.

Design

Secondary analysis of data from RCTs.

Setting

Academic medical centers.

Patient(s)

Women with polycystic ovary syndrome (PCOS) or couples with unexplained infertility, aged 18-40 years.

Intervention(s)

This study is not an intervention study, but the patients in the original RCTs were treated with any or combination of metformin, clomiphene citrate (CC), letrozole, and gonadotropins.

Main outcome measure(s)

Successful retention versus dropout during the RCTs.

Result(s)

Race, ethnicit

SUBMITTER: Kuang H 

PROVIDER: S-EPMC4630082 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature