Presence of Fleischer ring and prominent corneal nerves in keratoconus relatives and normal controls.

ABSTRACT:

Aim

To examine the occurrence of commonly known clinical signs of keratoconus (KC), i.e. Fleischer ring, prominent corneal nerves and thinning, among unaffected family members of KC patients and healthy control individuals.

Methods

Data of both eyes of 117 relatives of KC patients having no manifest disease based on videokeratography indices (KC relatives), and 142 controls were used for Pearson correlation and t-test statistics. Correlation of Fleischer ring, prominent corneal nerves and central pachymetry data were tested with each other and with videokeratography indices (KSI, KISA, 3 and 6 mm Fourier asymmetry, and I-S).

Results

A moderate correlation was found between Fleischer ring and all examined topographical indices. Most important correlation was present wi

SUBMITTER: Kriszt A 

PROVIDER: S-EPMC4631017 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature