VTE Incidence and Risk Factors in Patients With Severe Sepsis and Septic Shock.

ABSTRACT:

Background

Prospective studies on the incidence of VTE during severe sepsis and septic shock remain absent, hindering efficacy assessments regarding VTE prevention strategies in sepsis.

Methods

We prospectively studied 113 consecutively enrolled patients in the ICU with severe sepsis and septic shock at three hospitals. All patients provided informed consent. VTE thromboprophylaxis was recorded for all patients. Patients underwent ultrasonography and were followed for VTE prior to ICU discharge. All-cause 28-day mortality was recorded. Variables from univariate analyses that were associated with VTE (including central venous catheter [CVC] insertion, age, length of stay, and mechanical ventilation) were included in a multivariable logistic regression analysis using backward

SUBMITTER: Kaplan D 

PROVIDER: S-EPMC4631038 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature