Age-specific association of migraine with cryptogenic TIA and stroke: Population-based study.

ABSTRACT:

Objective

To determine whether there is an association between previous migraine and cryptogenic TIA or ischemic stroke at older ages.

Methods

We determined the age-specific associations of history of migraine and Trial of Org 10172 in Acute Stroke Treatment (TOAST) subtype of TIA and ischemic stroke in a population-based cohort study (Oxford Vascular Study; 2002-2012).

Results

Among 1,810 eligible patients with TIA or ischemic stroke, 668 (36.9%) had cryptogenic events, of whom 187 (28.0%) had previous migraine. Migraine was more commonly associated with cryptogenic events than with those of known etiology (odds ratio [OR] 1.73, 95% confidence interval [CI] 1.38-2.16, p < 0.0001; cardioembolic 2.00, 1.50-2.66, p < 0.0001; large artery 1.75, 1.20-2.53, p = 0.003; smal

SUBMITTER: Li L 

PROVIDER: S-EPMC4631068 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature