Gender difference in adiponectin associated with cardiovascular mortality.

ABSTRACT:

Background

It is important to identify cardiovascular diseases in patients at high risk. To include genetics into routine cardiological patients has therefore been discussed recently. We wanted to evaluate the association between high-molecular weight adiponectin and cardiovascular risk, and secondly in the same population evaluate if specific genotype differences regarding risk could be observed, and thirdly if gender differences could be seen.

Method

Four hundred seventy-six elderly participants recruited from a rural community were included. All participants underwent a clinical examination, echocardiography, and blood sampling and the single nucleotide polymorphism (SNP) (rs266729) of adiponectin was analysed. Follow-up time was 6.7 years.

Results

Those with high

SUBMITTER: Alehagen U 

PROVIDER: S-EPMC4631110 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature