Effects of smoking and preeclampsia on birth weight for gestational age.

ABSTRACT:

Objective

A counterintuitive interaction between smoking during pregnancy and preeclampsia on birth weight for gestational age (BWGA) outcomes was recently reported. In this report, we examine the relationship between these factors in a well-documented study population with exposure data on trimester of maternal smoking.

Methods

Preeclamptic (n = 238), gestational hypertensive (n = 219), and normotensive women (n = 342) were selected from live-births to nulliparous Iowa women. Disease status was verified by medical chart review, and smoking exposure was assessed by self-report. Fetal growth was assessed as z-score of BWGA. Multiple linear regression was used to test for the association of maternal smoking and preeclampsia with BWGA z-score.

Results

There was no intera

SUBMITTER: Spracklen CN 

PROVIDER: S-EPMC4631401 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature