MouseMove: an open source program for semi-automated analysis of movement and cognitive testing in rodents.

ABSTRACT: The Open Field (OF) test is one of the most commonly used assays for assessing exploratory behaviour and generalised locomotor activity in rodents. Nevertheless, the vast majority of researchers still rely upon costly commercial systems for recording and analysing OF test results. Consequently, our aim was to design a freely available program for analysing the OF test and to provide an accompanying protocol that was minimally invasive, rapid, unbiased, without the need for specialised equipment or training. Similar to commercial systems, we show that our software-called MouseMove-accurately quantifies numerous parameters of movement including travel distance, speed, turning and curvature. To assess its utility, we used MouseMove to quantify unilateral locomotor deficits in mice following t

SUBMITTER: Samson AL 

PROVIDER: S-EPMC4632026 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature