Severity of Remodeling, Myocardial Viability, and Survival in Ischemic LV Dysfunction After Surgical Revascularization.

ABSTRACT:

Objectives

This study sought to test the hypothesis that end-systolic volume (ESV), as a marker of severity of left ventricular (LV) remodeling, influences the relationship between myocardial viability and survival in patients with coronary artery disease and LV systolic dysfunction.

Background

Retrospective studies of ischemic LV dysfunction suggest that the severity of LV remodeling determines whether myocardial viability predicts improved survival with surgical compared with medical therapy, with coronary artery bypass grafting (CABG) only benefitting patients with viable myocardium who have smaller ESV. However, this has not been tested prospectively.

Methods

Interactions of end-systolic volume index (ESVI), myocardial viability, and treatment with respect to surv

SUBMITTER: Bonow RO 

PROVIDER: S-EPMC4633018 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature